| 1980 | Dr. Joseph F. Volker - "Medicine and Dentistry in the Colonies" |
| 1981 | Dr. Bengt E. Gustafsson - "Nomination and Selection Procedures for the Nobel Prize in Physiology or Medicine" |
| 1982 | Sir John Dewhurst, M.D. - "'Royal Confinements;' An Obstetrical History of the British Monarchy" |
| 1983 | Dr. Howard L. Holley - "Highlights in the History of Medicine in Alabama" |
| 1984 | Dr. Joachim S. Gravenstein - "Perspectives on Old Words and the History of Anesthesia" |
| 1985 | Dr. John W. Kirklin - "Lessons from the History of the Mayo Clinic" |
| 1986 | Dr. Charles A. Berry - "The Space Program and Medicine" |
| 1987 | Colonel Robert J. T. Joy, M.D. - "Dominique Jean Larrey: Surgeon to Napoleon's Guard" |
| 1988 | Dr. Roger Guillemin - "The Historical Description of Acromegaly One Hundred Years Ago: The Life and Times of Pierre Marie" |
| 1989 | Dr. Victor A. McKusick - "A Perspective on William Osler" |
| 1990 | Dr. Michael E. DeBakey - "The Development of Cardiovascular Surgery" |
| 1991 | Dr. Donald S. Frederickson - "Camelot-in-Bethesda: The Roots of the Magic Kingdom" |
| 1992 | Dr. Eli Ginzberg - "The Impact of World War II on U.S. Medicine" |
| 1993 | Dr. Harriet P. Dustan - "Health Reforms of the 1840s Cast Long Shadows" |
| 1994 | Dr. Constance S. Pittman - "Iodine and Iodination for One Billion People" |
| 1995 | Dr. Donald A. B. Lindberg - "A Brief and Biased History of Regional Medical Programs" |
| 1996 | Dr. Purnell W. Choppin - "From a Three-Headed Bit to the Nation's Largest Philanthropy: Howard Hughes, HHMI, and Biomedical Research" |
| 1997 | Dr. George D. Lundberg - "The Origins of the Peer Review Process and How it Works at J.A.M.A." |
| 1998 | Dr. Donald A. Henderson - "New and Emergent Epidemic Disease: The Past and the Future" |
| 1999 | Dr. Samuel O. Thier - "Academic Medicine at the Millennium" |
| 2000 | Dr. Arnold G. Diethelm - "Early Experience in Renal Transplantation: David, Joe, Roy and Tom" |
| 2001 | Dr. Jay Brooks Jackson - "The Use of Antiretrovirals for the Prevention of HIV Transmission: Past and Future" |
| 2002 | Dr. Gail H. Cassell - "Development of Antimicrobial Agents in the Era of New and Reemerging Infectious Diseases and Increasing Antibiotic Resistance" |
| 2003 | Dr. Max D. Cooper - "The Origin of the Immune System" |
| 2004 | Dr. James H. Thrall - "Scientific Reductionism and 21st Century Radiology" |
| 2005 | Dr. Karl M. Johnson - "Viral Hemorrhagic Fevers: From Yellow Jack to Ebola - and Beyond" |
| 2006 | Dr. Evan Yale Snyder - "Neural Stem Cells May Be Well Suited for CNS Repair" |
| 2007 | Dr. Basil I. Hirschowitz - "50 Years of Flexible Endoscopy" |
| 2008 | Dr. Stephen J. Greenberg - "Real Books: What They Are and Why We Still Need Them" |
| 2009 | Dr. W. Bruce Fye - "William Osler Leaves Johns Hopkins for Oxford: A Case Study of Physician Burnout a Century Ago" |
| 2010 | Dr. Barron H. Lerner - "When the Famous Get Sick and the Sick Get Famous: What We Do and Do Not Learn from Celebrity Patients." |
| 2011 | Dr. James K. Kirklin - "The History of Heart Transplantation and Mechanical Circulatory Support: A Revolution in Evolution" |
| 2012 | Dr. Carl R. Boyd - "The Assassination of Abraham Lincoln" |
| 2013 | Dr. Michael S. Saag - "Thirty Years of AIDS" |
| 2014 | Dr. Paul Lombardo - "America's Eugenic Legacy: 'A Peculiar and Lasting Appeal'" |
| 2015 | Dr. Bert Hansen - "Louis Pasteur and the Pleasures of Art" |
| 2016 | Dr. Kenneth M. Ludmerer - "Residency Training in the United States: Past, Present, Future" |
| 2017 | Dr. Howard J. Jacob - "Collaboration between UAB and HudsonAlpha for Precision and Personalized Medicine" |
| 2018 | Dr. Stephen M. Taylor - "The Opioid Crisis" |
| 2019 | Dr. H. Hughes Evans - "What Doctors Say and What Patients and Families Hear: Lessons from the History of Medicine and Pediatrics" |
| 2020 | Dr. Richard D. deShazo - "The Role of Organized Medicine in Present Day Health Disparities: From Nott to Now" |
| 2021 | Dr. Jeanne Marrazzo - "The COVID Pandemic in 2021: Where Have We Been and What Can We Expect?" |
| 2022 | Dr. Bruce R. Korf - "UAB Genomic Medicine" |
| 2023 | Dr. Jenny M. Luke - "A Century of Maternity Care: Alabama’s Highlights and Challenges" |
| 2024 | Dr. Jayme Locke - "Surgery, Science & Advocacy: Promoting Health Equity Across the Continuum of Transplant Care" |
